Biological Databases: A Comprehensive Overview
Biological databases store, organize, and provide access to vast amounts of molecular data including sequences, structures, and functional annotations.
Enzyme Databases: BRENDA and ExplorEnz
Enzyme databases provide comprehensive information about enzyme kinetics, substrates, inhibitors, and biochemical reactions.
Gene Expression Databases: GEO and ArrayExpress
Gene expression databases archive and distribute microarray and sequencing-based transcriptomics data for public reuse.
NCBI Databases: GenBank, RefSeq, and SRA
The National Center for Biotechnology Information hosts essential databases for nucleotide sequences, genomes, and sequencing read archives.
Pathway and Ontology Databases: KEGG, GO, and Reactome
Pathway and ontology databases systematically organize biological knowledge about molecular functions, cellular processes, and metabolic pathways.
UniProt and Protein Sequence Databases
UniProt provides a comprehensive resource for protein sequence and functional annotation, integrating data from numerous sources.
Variation Databases: dbSNP, ClinVar, and COSMIC
Variation databases catalog genetic variants across populations and their associations with disease, drug response, and phenotypes.