G Protein-Coupled Receptors
G protein-coupled receptors are the largest family of cell surface receptors, transmitting signals from hormones, neurotransmitters, and sensory stimuli through heterotrimeric G proteins.
Hormones and Their Classification
Hormones are chemical messengers secreted by endocrine glands that travel through the bloodstream to regulate the activity of distant target tissues.
JAK-STAT Signaling Pathway
The JAK-STAT signaling pathway transmits signals from cytokines, interferons, and growth factors to the nucleus, regulating gene expression in immune responses and cell growth.
Receptor Types and Mechanisms
Cellular receptors are proteins that bind signaling molecules and initiate intracellular responses, classified into four main types based on their structure and mechanism.
Receptor Tyrosine Kinases
Receptor tyrosine kinases are a class of enzyme-linked receptors that regulate cell growth, differentiation, metabolism, and survival through tyrosine phosphorylation.
Second Messengers
Second messengers are small intracellular signaling molecules that relay and amplify signals from cell surface receptors to intracellular targets.
Wnt, Notch, and Hedgehog Signaling
Wnt, Notch, and Hedgehog are three highly conserved signaling pathways that control cell fate decisions, embryonic development, and tissue homeostasis.