Clinical Enzymology
Clinical enzymology uses measurements of enzyme activity in blood and other body fluids to diagnose disease, monitor disease progression, and assess treatment response.
Coenzymes and Cofactors
Coenzymes and cofactors are non-protein components that many enzymes require for catalytic activity, serving as carriers of electrons, atoms, or functional groups.
Enzyme Classification and Nomenclature
Enzymes are classified by the International Union of Biochemistry and Molecular Biology into six main classes based on the type of reaction they catalyze.
Enzyme Inhibition
Enzyme inhibition is a key regulatory mechanism and the basis for many pharmaceutical drugs, with reversible and irreversible inhibition strategies.
Enzyme Mechanisms of Catalysis
Enzymes accelerate chemical reactions by lowering the activation energy through several catalytic strategies including acid-base, covalent, and metal-ion catalysis.
Enzyme Regulation
Enzyme activity is regulated through multiple mechanisms including allosteric regulation, covalent modification, zymogen activation, and control of enzyme quantity.