Primer Design for PCR and Sequencing
Primer design creates short oligonucleotides with optimal thermodynamics and specificity for PCR amplification and sequencing reactions.
Sequence AnalysisPromoter Analysis: Identifying Regulatory Regions
Promoter analysis identifies transcription start sites and regulatory elements that control gene expression.
Sequence AnalysisSequence Alignment: Pairwise Comparison of Biological Sequences
Sequence alignment arranges DNA, RNA, or protein sequences to identify regions of similarity and evolutionary relationships.
Sequence AnalysisSequence Assembly: Reconstructing DNA from Fragments
Sequence assembly algorithms merge overlapping DNA fragments into contiguous sequences for genome and transcriptome reconstruction.
Sequence AnalysisSequence Database Search with BLAST
BLAST finds regions of local similarity between query sequences and database entries for functional and evolutionary inference.
Sequence AnalysisBinding Site Prediction: Identifying Functional Regions
Binding site prediction identifies regions on proteins that interact with ligands, substrates, or other macromolecules.
Structural BioinformaticsComputational Protein Design: Engineering Novel Proteins
Computational protein design creates novel protein sequences that fold into desired three-dimensional structures with specific functions.
Structural BioinformaticsCryo-EM Structure Analysis: Computational Processing
Cryo-electron microscopy structure analysis uses computational methods to reconstruct three-dimensional macromolecular structures from microscopic images.
Structural BioinformaticsMolecular Docking: Predicting Ligand-Receptor Interactions
Molecular docking predicts the preferred orientation and binding affinity of a ligand to a protein receptor.
Structural Bioinformatics