Neurodegenerative Disease Pathology
Neurodegenerative diseases are characterized by progressive loss of neuronal populations and accumulation of abnormal protein aggregates in the brain.
HistologyStains for Myelin, Neurons and Glia
Special stains and immunohistochemistry visualize myelin, neurons and glial cells in nervous tissue for diagnosing demyelinating and degenerative diseases.
HistologyAmyloid, Pigment and Mineral Stains
Histochemical stains for amyloid, endogenous pigments and mineral deposits identify these substances in tissue sections for specific diagnosis.
HistologyCarbohydrate and Mucin Histochemistry
Carbohydrate and mucin stains detect glycogen, glycoproteins, proteoglycans and mucins in tissue sections for diagnostic histochemistry.
HistologyConnective Tissue and Muscle Stains
Connective tissue stains differentially color collagen, elastic fibers, muscle and fibrin to evaluate fibrosis, vascular disease and tissue injury.
HistologyH&E: Formulation, Chemistry and Troubleshooting
Hematoxylin and eosin is the standard tissue stain; its chemistry and formulation determine nuclear detail and cytoplasmic contrast.
HistologyStains for Microorganisms in Tissue
Histochemical stains for microorganisms enable visualization of bacteria, fungi, mycobacteria and parasites in formalin-fixed tissue sections.
HistologyAutomated Tissue Processing: Protocols, Reagents and Troubleshooting
Automated tissue processors dehydrate, clear and infiltrate fixed tissue with paraffin wax through programmed cycles of reagent exchanges.
HistologyDecalcification Techniques
Decalcification removes calcium from mineralized tissue to enable sectioning, using acids or chelating agents that must preserve morphology and antigenicity.
Histology