Fibrinogen and D-Dimer Testing
Fibrinogen and D-dimer are key coagulation parameters used to assess bleeding risk, diagnose DIC, and exclude venous thromboembolism.
Introduction to Hemostasis
Hemostasis is the physiological process that stops bleeding at sites of vascular injury while maintaining blood fluidity in the circulation.
Prothrombin Time, INR, and Activated Partial Thromboplastin Time
PT/INR and aPTT are the most commonly ordered coagulation screening tests, evaluating the extrinsic and intrinsic pathways respectively.
The Coagulation Cascade
The coagulation cascade is a series of enzymatic reactions leading to fibrin clot formation, organized into intrinsic, extrinsic, and common pathways.
von Willebrand Factor and Platelet Function Tests
von Willebrand factor mediates platelet adhesion and carries factor VIII; its deficiency causes the most common inherited bleeding disorder.
