Hemoglobinopathies: Sickle Cell Disease and Thalassemia
Hemoglobinopathies are genetic disorders of hemoglobin structure or synthesis, including sickle cell disease and the thalassemias.
Hemolytic Anemias
Hemolytic anemias result from premature destruction of RBCs, classified by site of hemolysis and underlying etiology.
Iron Deficiency Anemia
Iron deficiency anemia is the most common nutritional deficiency worldwide, characterized by microcytic hypochromic RBCs and depleted iron stores.
Megaloblastic Anemias
Megaloblastic anemias result from vitamin B12 or folate deficiency, causing impaired DNA synthesis and macrocytic anemia with distinctive morphologic features.
Classification of Anemias
Anemia is classified by RBC morphology and underlying mechanism, guiding the laboratory workup and differential diagnosis.
