Sequence Database Search with BLAST
BLAST finds regions of local similarity between query sequences and database entries for functional and evolutionary inference.
BioinformaticsBinding Site Prediction: Identifying Functional Regions
Binding site prediction identifies regions on proteins that interact with ligands, substrates, or other macromolecules.
BioinformaticsComputational Protein Design: Engineering Novel Proteins
Computational protein design creates novel protein sequences that fold into desired three-dimensional structures with specific functions.
BioinformaticsCryo-EM Structure Analysis: Computational Processing
Cryo-electron microscopy structure analysis uses computational methods to reconstruct three-dimensional macromolecular structures from microscopic images.
BioinformaticsMolecular Docking: Predicting Ligand-Receptor Interactions
Molecular docking predicts the preferred orientation and binding affinity of a ligand to a protein receptor.
BioinformaticsMolecular Dynamics Simulations of Biomolecules
Molecular dynamics simulations model the physical movements of atoms and molecules over time to study biomolecular behavior.
BioinformaticsProtein Structure Comparison and Alignment
Protein structure comparison aligns three-dimensional structures to identify evolutionary relationships and functional similarities.
BioinformaticsProtein Structure Prediction: From Sequence to Structure
Protein structure prediction computationally determines three-dimensional protein structures from amino acid sequences using homology modeling and deep learning.
BioinformaticsRNA Structure Prediction: From Sequence to Shape
RNA structure prediction computationally determines secondary and tertiary structures of RNA molecules from their nucleotide sequences.
Bioinformatics