Clinical Enzymology
Clinical enzymology uses measurements of enzyme activity in blood and other body fluids to diagnose disease, monitor disease progression, and assess treatment response.
BiochemistryCoenzymes and Cofactors
Coenzymes and cofactors are non-protein components that many enzymes require for catalytic activity, serving as carriers of electrons, atoms, or functional groups.
BiochemistryEnzyme Classification and Nomenclature
Enzymes are classified by the International Union of Biochemistry and Molecular Biology into six main classes based on the type of reaction they catalyze.
BiochemistryEnzyme Inhibition
Enzyme inhibition is a key regulatory mechanism and the basis for many pharmaceutical drugs, with reversible and irreversible inhibition strategies.
BiochemistryEnzyme Mechanisms of Catalysis
Enzymes accelerate chemical reactions by lowering the activation energy through several catalytic strategies including acid-base, covalent, and metal-ion catalysis.
BiochemistryEnzyme Regulation
Enzyme activity is regulated through multiple mechanisms including allosteric regulation, covalent modification, zymogen activation, and control of enzyme quantity.
BiochemistryCholesterol Metabolism
Cholesterol is an essential sterol that modulates membrane fluidity and serves as a precursor for bile acids, steroid hormones, and vitamin D.
BiochemistryEicosanoids
Eicosanoids are signaling molecules derived from arachidonic acid that mediate inflammation, fever, pain, blood clotting, and smooth muscle contraction.
BiochemistryLipid Structure and Classification
Lipids are a diverse group of hydrophobic or amphipathic molecules that serve as energy stores, structural components of membranes, and signaling molecules.
Biochemistry