The Endomembrane System and Protein Trafficking
The endomembrane system is a network of membrane-bound organelles that synthesize, modify, sort, and transport proteins and lipids throughout the eukaryotic cell.
Biology
Chromosome Structure and Organization
Chromosomes are highly organized structures of DNA and proteins that package genetic information and regulate gene expression within the cell nucleus.
BiologyMendelian Genetics and Inheritance Patterns
Mendelian genetics describes the fundamental principles of inheritance through dominant and recessive alleles, segregation, and independent assortment of genes.
Biology
The Complement System
The complement system is a cascade of serum proteins that opsonizes pathogens, recruits inflammatory cells, and directly lyses microbes through the membrane attack complex.
BiologyCytokines and Chemokines
Cytokines and chemokines are small signaling proteins that mediate intercellular communication in the immune system, regulating inflammation, immunity, and hematopoiesis.
Biology
Antiviral Immune Responses
Antiviral immune responses encompass the innate and adaptive mechanisms by which the host detects, restricts, and eliminates viral infections.
Biology
Capillary Electrophoresis: Principles and Instrumentation
Capillary electrophoresis is a separation technique that uses narrow capillaries and high-voltage electric fields to separate charged analytes based on their electrophoretic mobility.
ChemistryCapillary Gel Electrophoresis: Size-Based Separation in Polymer Matrices
Capillary gel electrophoresis uses a polymer gel or linear polymer matrix within a fused-silica capillary to separate DNA, RNA, and proteins by molecular size with high resolution.
ChemistryCapillary Isoelectric Focusing
Capillary isoelectric focusing separates amphoteric molecules such as proteins and peptides according to their isoelectric point in a pH gradient established within the capillary.
ChemistryCapillary Isotachophoresis: Principles and Applications
Capillary isotachophoresis is an electrophoretic technique that uses a discontinuous buffer system to focus analytes into sharp, concentrated zones that migrate at equal velocity.
ChemistryCapillary Zone Electrophoresis
Capillary zone electrophoresis separates analytes in free solution based on differences in their electrophoretic mobility under an applied electric field.
ChemistryMicellar Electrokinetic Chromatography: Principles and Applications
Micellar electrokinetic chromatography is a capillary electrophoresis technique that uses surfactant micelles as a pseudostationary phase to separate neutral and charged analytes by hydrophobic partitioning and electrophoretic migration.
Chemistry