Plasma Cell Disorders
Plasma cell disorders are clonal proliferations of immunoglobulin-secreting plasma cells, ranging from benign monoclonal gammopathy to multiple myeloma.
HematologyClassification of Anemias
Anemia is classified by RBC morphology and underlying mechanism, guiding the laboratory workup and differential diagnosis.
HematologyBlood Component Therapy
Blood component therapy involves the separation of whole blood into components for targeted transfusion to correct specific deficits.
HematologyTransfusion Reactions and Adverse Events
Transfusion reactions range from mild febrile responses to life-threatening hemolytic reactions requiring immediate recognition and intervention.
HematologyFibrinogen and D-Dimer Testing
Fibrinogen and D-dimer are key coagulation parameters used to assess bleeding risk, diagnose DIC, and exclude venous thromboembolism.
HematologyIntroduction to Hemostasis
Hemostasis is the physiological process that stops bleeding at sites of vascular injury while maintaining blood fluidity in the circulation.
HematologyProthrombin Time, INR, and Activated Partial Thromboplastin Time
PT/INR and aPTT are the most commonly ordered coagulation screening tests, evaluating the extrinsic and intrinsic pathways respectively.
HematologyThe Coagulation Cascade
The coagulation cascade is a series of enzymatic reactions leading to fibrin clot formation, organized into intrinsic, extrinsic, and common pathways.
Hematologyvon Willebrand Factor and Platelet Function Tests
von Willebrand factor mediates platelet adhesion and carries factor VIII; its deficiency causes the most common inherited bleeding disorder.
Hematology