Fluorescence In Situ Hybridization
Fluorescence in situ hybridization uses fluorescently labeled DNA probes to detect and localize specific DNA sequences on chromosomes and in interphase nuclei.
BiochemistryIn Situ Hybridization
In situ hybridization uses labeled complementary DNA or RNA probes to detect and localize specific nucleic acid sequences within intact cells, tissues, or chromosomes.
BiochemistryPhage Display
Phage display is a molecular biology technique that displays foreign peptides or proteins on the surface of bacteriophage particles, enabling selection and evolution of molecules with desired binding properties.
BiochemistryNMR Spectroscopy
Nuclear magnetic resonance spectroscopy determines the three-dimensional structure and dynamics of proteins and other biomolecules in solution at atomic resolution.
Biochemistry2D-PAGE
Two-dimensional polyacrylamide gel electrophoresis separates complex protein mixtures by isoelectric point in the first dimension and molecular weight in the second dimension.
BiochemistryX-ray Crystallography
X-ray crystallography determines the three-dimensional atomic structure of proteins and other macromolecules by analyzing diffraction patterns from crystalline samples.
Biochemistry
Cell Death: Apoptosis, Necrosis, and Autophagy
Cell death occurs through distinct mechanisms including apoptosis, necrosis, and autophagy, each with unique molecular pathways and roles in development, homeostasis, and disease.
Cell biologyStem Cells and Regenerative Medicine
Stem cells are undifferentiated cells capable of self-renewal and differentiation into specialized cell types, with applications in regenerative medicine, disease modeling, and drug discovery.
Cell biologyNon-coding RNAs and Gene Regulation
Non-coding RNAs, including microRNAs, long non-coding RNAs, and circular RNAs, regulate gene expression at transcriptional and post-transcriptional levels and are implicated in development and disease.
Genetics